Lung Cancer

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Curie Research by Curie Oncology

Clinical Trial – Lung Cancer

Protocol Name / No.Protocol TitlePrincipal Investigator
SOHO-02A phase 3 open-label, randomized, active-controlled, multicenter trial to evaluate efficacy and safety of BAY 2927088 in comparison with SOC as a first-line therapy in patients with unresectable, locally advanced or metastatic NSCLC with HER2 activating mutations

NCT number:
https://clinicaltrials.gov/study/NCT06452277
Dr Toh Chee Keong
KRYSTAL7A Phase 2 Trial of Adagrasib Monotherapy and in Combination with Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination with Pembrolizumab versus Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (849-007)

NCT number:
https://clinicaltrials.gov/study/NCT04613596
Dr Toh Chee Keong
FURMO-006A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared With Investigator’s Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer With Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)

NCT number:
https://clinicaltrials.gov/study/NCT07185997
Dr Toh Chee Keong